As Americans wake up to news that their president has spent the night in hospital, let's look at other ways the global pandemic is marking our lives this weekend, in the UK and other countries.
Sunday's London Marathon will look worlds away from previous editions, the BBC's Alice Evans reports.
The UK's coronavirus lockdown forced a six-month delay to the race, which is normally run in April. Only a handful of runners, all elite, will be taking part on the official course around St James's Park in central London.
Gill Silverthorn said she had had a few odd looks from people while training for her race - which will take place along coastal paths and promenades around Penzance, Cornwall - wearing her 10kg rhino costume.
And in Brisbane, 10,000 miles (16,000km) away from the usual starting line in Greenwich, south-east London, Elizabeth Gallagher will begin her marathon at 3am UK time (midday for her).
Chris Finill, one of the "Ever Presents", a group of just 10 people who have run every London Marathon, will be running laps of Dunsfold Aerodrome in Surrey instead of the usual course for the 40th time.
The 61-year-old said: "It will be more meaningful to get to the finish on Sunday than it would be in a normal year because most people's journeys to get to the start line have been pretty difficult - let alone the race itself.
"So I think we'll all feel a particular sense of relief and satisfaction when we cross that finish line."
Across the UK, students are self-isolating in their accommodation after outbreaks at university, with the 770 confirmed cases at Northumbria University among the largest clusters of infections.
It's prompted protests from many students, including at Edinburgh University's Pollock Halls, a complex which holds 1,880 people. Social media accounts called pollockprisoner have dubbed it "the UK's most expensive prison".
A student, Eve, told BBC Radio 4's Today programme that one block was "completely locked down" and students were only allowed to leave their rooms once during the self-isolation period to take out their bins and do washing.
She said meals were delivered haphazardly, sometimes with breakfast, lunch and dinner all arriving at 21:00, while pastoral care was "really quite shocking" as students faced waiting days for a response from the university.
Edinburgh vice-chancellor Prof Peter Mathieson said: "We’re very keen to listen to our students and to respond to their concerns."
He said that when they delivered over a thousand meals, they only received a handful of complaints. "The majority are satisfied," he said.
Mathieson said the university had no plans to refund tuition fees, which are over £9,000 ($11,600) a year for students from parts of the UK other than Scotland. "An Edinburgh degree will still be a fantastic investment for these students," he said.
Donald Trump has been given two experimental drugs after testing positive for COVID-19.
White House doctor Sean Conley said the president was given a dose of an antibody drug being developed by Regeneron on Friday before he was taken to a military hospital where he has started remdesivir therapy.
The president appeared upbeat as he landed at the Walter Reed Military Hospital in Maryland on Friday evening despite developing fatigue symptoms and having trouble breathing, according to an adviser.
Sky News looks at what remdesivir and Regeneron's drug do, and how effective they have been in trials.
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Trump: 'I think I'm doing very well'
What is remdesivir?
A drug that once offered hope in the treatment of Ebola, remdesivir is an antiviral medicine that has not been approved anywhere in the world for any use.
More from Covid-19
It is injected into the vein in the hope it will prevent SARS CoV-2 (the virus that causes COVID-19) from multiplying in the body, with some patients recovering faster after using it.
Gilead Sciences Inc began research on remdesivir in 2009 as part of studies into hepatitis C and respiratory syncytial virus (RSV), a common and highly contagious respiratory virus that most children get before they turn two.
After scientists in China determined the new pneumonia-like illness was caused by a coronavirus, Gilead provided remdesivir to China to test the drug against the virus.
Remdesivir is thought to interfere with the mechanism that certain viruses use to make copies of themselves, but scientists are still determining how that occurs.
Several clinical trials and laboratory studies have taken place since January, with some promising signs.
However, a report published in The Lancet medical journal on 3 October looking at several studies has found remdesivir "did not appear to affect rates of SARS CoV-2 viral load decline and mortality".
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Do Americans feel sorry for Trump?
It said using remdesivir early "substantially decreased" viral loads but this effect was "completely lost" when the drug was given just eight hours after infection.
The report concluded that remdesivir "might require initiation before the peak viral replication" but that is "not feasible" in humans as they display symptoms after the virus multiplies.
It added that there is no clinical reason why remdesivir could not be administered before someone shows symptoms.
What is the experimental Regeneron treatment?
Drug maker Regeneron provided a dose of its experimental antibody treatment to the president on Friday before the decision to take him to Walter Reed was made.
Still in large-scale clinical trials, the new antiviral antibody "cocktail" works by binding to a protein on the surface of the virus.
This is meant to stop the virus from attaching to cells and replicating, while allowing the immune system to attack the virus.
Mr Trump was given a single 8g dose, which should "last for quite a long time", Regeneron chief executive Dr Leonard Schleifer told CNN.
Last weekend, the drug started being used in "about three hospitals in the north" of England as part of Oxford University's national recovery trial, Professor Peter Horby told the BBC.
The specialist in emerging infectious diseases at the University of Oxford said the drug is "very promising" and "very potent".
This class of drugs is "pretty safe and well understood" so is something he has "confidence in", he said.
He added that about four or five hundred patients have been given it so far and there have been "no worrying safety signals", with the plan to roll it out to another 30 to 40 UK hospitals next week.
Prof Horby said a single dose of the treatment provides "prolonged protection" for "a month to six weeks".
Dr Jeremy Faust, an emergency doctor at Brigham and Women's Hospital in Boston, said he would not give it to his patients because he could not say what the benefit is, or the risks.
He added that giving an unproven treatment to the president "sends a message that they're scrambling".
Several cases have been confirmed among those who have had close contact with Donald Trump and his aide Hope Hicks, whose diagnosis prompted the test that confirmed the US president had the coronavirus.
The period between infection and sickness can be anything from a few days to two weeks, so he could have contracted it on a number of occasions and from a variety of people.
Here is a summary of some of those involved so far:
Positive tests:
Donald Trump, 74
US president since 2016, he has seen his campaign effectively put on hold after testing positive for COVID-19.
He was at the White House Rose Garden last Saturday 26 September to announce the nomination of Judge Amy Coney Barrett to the Supreme Court. He attended a rally in Pennsylvania on Saturday night, and another event in Ohio on Monday.
Image:On 26 September Donald Trump held an event in the Rose Garden to announce his nominee for the Supreme Court
He was at a fundraiser and rally on Wednesday in Minnesota, where he did a shorter speech than usual.
By Thursday morning Mr Trump would have been aware of the positive test result for Hope Hicks. Despite this, he went ahead with a fundraising trip to his golf club in New Jersey. According to public health guidelines he should have isolated, having been in close proximity to someone infected with the virus.
In the early hours of Friday, after returning from the New Jersey event, he tweeted to say he and his wife had tested positive and were in isolation.
Image:Hope Hicks
Hope Hicks, 31
Presidential adviser and former White House communications director. She is a close confidante to Mr Trump.
Ms Hicks was not at the Rose Garden event on 26 September.
She was part of the team who travelled with Mr Trump to Cleveland for the presidential debate on Tuesday. She returned a negative test on Wednesday morning and joined others for the trip to Minnesota that day. It was in Minnesota that she reported feeling unwell.
She stayed apart from others on the first leg of the journey (by plane) and did not take the crowded Marine One back to the White House. On Thursday morning her test was positive. Those who had been near her were not immediately told.
Image:Melania Trump
Melania Trump, 50
First lady, wife of Donald Trump.
She often travels with her president husband and she was at the Rose Garden event in late September.
Her diagnosis was announced at the same time as her husband's on Friday 2 October.
She tweeted later in the day that she was experiencing "mild symptoms" and was "overall feeling good", adding: £"I am looking forward to a speedy recovery."
Image:Kellyanne Conway
Kellyanne Conway, 53
Former presidential adviser who left the White House in August.
She was at the Rose Garden event on Saturday, sitting in the front row.
Pictures of the event showed a few hundred people sitting close to each other, many without masks, including Mrs Conway.
She tweeted: "My symptoms are mild (light cough) and I'm feeling fine."
Image:Amy Coney Barrett with Mike Lee on 29 September
Senator Mike Lee, 49
Republican from Utah, Mr Lee was also at the Rose Garden last Saturday and met Amy Coney Barrett, who was announced as Mr Trump's pick for the vacant seat on the US Supreme Court, a few days later.
He announced he had tested positive for COVID-19 on Friday, after a negative result earlier in the week.
Image:Thom Tillis
Senator Thom Tillis, 60
Republican from North Carolina and a member of the Judiciary Committee.
He had a negative test before attending the White House Rose Garden event on Saturday and he met Mr Trump's Supreme Court nominee Ms Coney Barrett on Wednesday. Mr Tillis was pictured wearing a mask at the Saturday event, but not at the Wednesday meeting.
On Thursday night he took part in a debate with the Democratic challenger for his senate seat, Cal Cunningham. Both wore masks.
Mr Tillis revealed his positive test result on Friday. Mr Cunningham has said he will get tested.
Image:John Jenkins
John Jenkins, 65
President of the University of Notre Dame, Mr Jenkins is another person who was at the Rose Garden event last Saturday and who announced his positive test result on Friday.
The university's vice president Paul Browne said in a statement that Mr Jenkins had "learned that a colleague with whom he has been in regular contact tested positive for COVID-19".
Image:Bill Stepien
Bill Stepien, 42
The president's campaign manager has also tested positive for the coronavirus and is experiencing "mild flu-like symptoms".
Mr Trump's immediate campaign events have all been cancelled, and his next debate with Democrat Joe Biden, scheduled for 15 October, is now in question.
Three journalists
The trio tested positive on Friday after spending last weekend at the White House or travelling with Mr Trump, according to Zeke Miller, president of the White House Correspondents' Association.
Negative tests:
Image:Joe Biden
Joe Biden, 77
Democratic presidential candidate, Mr Biden debated with Mr Trump in Cleveland on Tuesday.
Unlike Mr Trump, Mr Biden has regularly worn a mask when in public. However, during the exchanges, he was not wearing one.
Many people in the audience, including Mr Trump's family members, were also not wearing masks.
Both Mr Biden and his wife Jill tested negative on Friday.
Image:Kamala Harris
Kamala Harris, 55
Mr Biden's running mate, candidate for vice president, had a routine test and the result was negative on Thursday.
Image:Amy Coney Barrett
Amy Coney Barrett, 48
Mr Trump's nominee for the Supreme Court was at the Rose Garden event on 26 September to accept her Supreme Court nomination.
She recovered from a confirmed case of the coronavirus earlier this year.
Image:Mike Pence
Mike Pence, 61
The US vice president and his wife Karen tested negative on Friday morning.
According to reports, Mr Pence was in the Oval Office with the president on Tuesday and was last publicly seen with him at a Monday news conference.
Image:William Barr
William Barr, 70
The US Attorney General was at the Rose Garden event on 26 September and was seen without a mask, speaking with Mrs Conway, but he tested negative on Friday, a Department of Justice spokesperson said.
Donald Trump was reportedly ‘spooked’ by his worsening coronavirus symptoms shortly before he headed to the Walter Reed Medical Center Friday (Pictures: AP)
Donald Trump grew ‘spooked’ by his coronavirus diagnosis as he began struggling to breathe, insiders said, amid warnings the president’s condition is ‘serious.’ The President of the United States fears for his own health were revealed as he was helicoptered to Walter Reed Medical Center in Maryland Friday evening.
Trump, who is set to spend ‘a few days’ at the military hospital, reportedly grew increasingly alarmed as his symptoms worsened over the course of Friday, a source told CNN. The president is said to have suffered nasal congestion that left him struggling to breathe, a fever and severe fatigue.
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An aide said that while Trump appears to be in good health at the minute, White House staff are keenly aware that coronavirus patients can take a sudden and serious turn for the worse.
Trump remains in charge of the United States, although the 25th Amendment of the US Constitution may be used to transfer power to Mike Pence if he becomes incapacitated. Pence tested negative for Covid earlier on Friday.
Trump walked himself out to his Marine One helicopter on Friday evening – and gave a small wave for the camera – after sharing a video to Twitter insisting that he would be fine. Trump said: ‘I want to thank everybody for the tremendous support. I’m going to Walter Reed hospital. I think I’m doing very well.
‘But we’re going to make sure that things work out. The first lady is doing very well. So thank you very much, I appreciate it, I will never forget it – thank you.’ The president was admitted to hospital around 14 hours after he revealed he had tested positive for coronavirus.
Trump, who wore a navy mask for Friday’s helicopter flight, later disembarked the chopper solo, while holding onto its handrail. His diagnosis marks a sudden and shocking development in an election campaign already fraught with drama ahead of the November 3 election, with voting already underway via mail-in ballots.
On Friday evening, Fox News host Chris Wallace – who hosted Tuesday’s presidential debate between Trump and Joe Biden – revealed the president and his party turned up too late to get pre-broadcast Covid tests.
Trump was allowed to take to the stage by making use of the event’s honor system. The president receives regular coronavirus tests, and is a self-confessed germaphobe, with a Supreme Court nomination event held at the White House last Saturday believed to be a possible source for the spread.
Trump leaves the White House to travel to Walter Reed Medical Center on Friday afternoon (Picture: EPA)
Marine One flies out of the White House garden and past the Washington Monument to Walter Reed Medical Center with President Trump on board (Picture: AP)
Trump was seen disembarking at Walter Reed shortly afterwards. Aides say he plans to stay at the military hospital for several days (Picture: EPA)
The president was given an experimental antibody treatment called Regeneron Friday evening, in a bid to protect his immune system from the worst effects of Covid-19, which has so-far infected 7.2million Americans, and killed over 107,000.
Trump’s election rival Joe Biden tested negative for coronavirus on Friday morning. The president is feared to have been infected at a White House garden party last Saturday which saw him unveil his new Supreme Court nominee Amy Barrett.
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Five high profile attendees – Trump, his wife Melania, Trump’s aide Hope Hicks, as well as Senators Mike Lee and Thom Tillis have all since tested positive for coronavirus. Attendees were filmed gathered closely in the garden, and were snapped hugging and kissing one another without wearing face masks.
Trump – who is 74 years-old and obese – is in the ‘at risk’ category for serious complications from coronavirus.
President Trump is seen returning from his New Jersey golf club Thursday, hours before announcing he’d tested positive for coronavirus (Picture: AP)
His aides say he will continue to work from special presidential offices at Walter Reed Medical Center, with the US presidential election just 32 days off.
Melania Trump has mild symptoms of Covid, including a headache and fatigue, and has not required hospital treatment.
Former presidents Barack Obama and Bill Clinton are among those who have sent Trump their best wishes, with election rival Joe Biden also wishing the president a speedy recovery.
Voting by mail has already begun for the November 3 presidential election.
Trump’s name could still end up being on the presidential ballot even if he is incapacitated in the coming weeks, sparking meetings in the White House about how to deal with the unprecedented crisis.
US President Donald Trump is being flown to hospital less than 24 hours after testing positive for coronavirus.
The White House said the decision to transport him to Walter Reed National Military Medical Center was taken "out of an abundance of caution".
Mr Trump began exhibiting "mild symptoms" of Covid-19 on Thursday after disclosing that he and his wife had gone into quarantine late Wednesday.
The White House said he was feeling "fatigued but in good spirits".
Wearing a mask and suit, the president walked out across the White House lawn on Friday afternoon to his helicopter, Marine One, for the short trip to hospital.
He waved and gave a thumbs-up to reporters but said nothing before boarding the aircraft.
The news comes just over a month before presidential elections, where he will face Democratic challenger Joe Biden.
What is the White House saying?
A White House spokesperson said in a statement: "President Trump remains in good spirits, has mild symptoms, and has been working throughout the day.
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"Out of an abundance of caution, and at the recommendation of his physician and medical experts, the president will be working from the presidential offices at Walter Reed for the next few days.
"President Trump appreciates the outpouring of support for both he and the first lady."
Mr Trump's symptoms include a low-grade fever, according to the BBC's US partner, CBS News.
Walter Reed, in the Washington DC suburbs, is one of America's largest and most renowned military medical centres. It is where US presidents usually go for their annual check-ups.
White House communications director Alyssa Farah said the president had not transferred his powers to Vice-President Mike Pence.
"The president is in charge," she said.
Under the US constitution, if Mr Trump did become too ill to carry out his duties, he could hand over his powers to the vice-president temporarily. That means Mike Pence would become acting president until Mr Trump was fit again and could resume work.
A fundamentally altered contest
The US presidential election has been turned on its head.
That sentence could have been written about any number of moments in a tumultuous year in American politics, but nothing quite like this has occurred this year, this decade, this century.
Just 32 days before the presidential election, Donald Trump has tested positive for Covid-19. Given his age, 74, he is in a high-risk category for complications from the disease. At the very least, he will have to quarantine while he is treated, meaning the US presidential contest - at least his side of it - has been fundamentally altered.
The initial implications are obvious. The president's rigorous campaign schedule - which included visits to Minnesota, Pennsylvania, Virginia, Georgia, Florida and North Carolina in just the past week - is on indefinite hold.
Trump will certainly have surrogates on the trail for him, but given that he has relied heavily on his family and senior administration and campaign officials for such tasks in the past, and many of them may have to quarantine because of their own exposure to the virus, that campaign operation will be disrupted as well.
What treatment has the president received at the White House?
Mr Trump's physician Sean Conley said in a statement earlier on Friday that the president had "as a precautionary measure received an 8g dose of Regeneron's polyclonal antibody cocktail" at the White House. The medication is administered to help reduce virus levels and speed recovery.
He was also taking zinc, vitamin D, famotidine, melatonin and aspirin, Dr Conley said.
"As of this afternoon he remains fatigued but in good spirits," he added. The first lady was "well with only a mild cough and headache".
How has the Biden campaign reacted?
Mr Biden himself and his wife Jill tested negative on Friday.
"I hope this serves as a reminder," the Democratic White House candidate tweeted after the result. "Wear a mask, keep social distance, and wash your hands."
The Biden campaign said it was in the process of temporarily taking down all its negative ads regarding Mr Trump.
Mr Biden's staff said he would travel to Michigan on Friday as planned for several campaign events. He and his wife have wished the presidential couple a speedy recovery.
What next?
Officials said the process of tracking all the president's contacts in recent days was ongoing, adding that Mr Trump was considering how he might address the nation or otherwise communicate with the American people on Friday.
But he pulled out of a video conference call with vulnerable seniors scheduled for Friday, leaving Vice-President Mike Pence to chair the meeting.
On Thursday, the first couple said they intended to self-isolate after one of Mr Trump's closest aides, Hope Hicks, tested positive. Soon afterwards, they too received positive test results.
There has been criticism of Mr Trump's decision to go to a fundraiser attended by dozens of people in New Jersey on Thursday, apparently when officials already knew about Ms Hicks' symptoms.
